Avoiding Medications for Von Willebrand Disease: Important Considerations
Headline: Important Medication and Supplement Considerations for People with Von Willebrand Disease (VWD)
Von Willebrand disease (VWD) is a bleeding disorder that affects blood clotting. People with VWD should be mindful of medications and supplements that could increase bleeding risk or interfere with blood clotting.
Body:
People with VWD should avoid certain medications and supplements that pose a higher bleeding risk. These include:
- Aspirin and other antiplatelet drugs, such as clopidogrel, which prevent platelet aggregation and increase bleeding risk.
- Nonsteroidal anti-inflammatory drugs (NSAIDs), like ibuprofen and naproxen, as they impair platelet function and can cause more bruising and bleeding.
- Anticoagulants (blood thinners), including warfarin, heparin, and newer oral anticoagulants (apixaban, rivaroxaban), that directly affect clotting mechanisms.
- Corticosteroids, such as prednisone, when used long-term can weaken blood vessels and thin the skin, increasing bleeding risk.
- Certain supplements with blood-thinning effects, such as fish oil, ginkgo biloba, garlic, and high doses of vitamin E.
In addition, people with VWD should use caution with skin and mouth care to avoid trauma that can provoke bleeding. This includes using soft toothbrushes and electric shavers, and avoiding activities likely to cause bruises or cuts.
Desmopressin, a common treatment for mild bleeds in people with VWD, promotes the release of von Willebrand factor and factor VIII into the bloodstream. However, Desmopressin can interact dangerously with loop diuretics or corticosteroids, increasing the risk of severe hyponatremia, so these combinations should be avoided or used cautiously under medical supervision.
Conclusion:
In summary, aspirin, NSAIDs, anticoagulants, corticosteroids, and certain supplements that thin the blood should be avoided or used with caution in Von Willebrand disease due to bleeding risks. People with VWD should always consult their healthcare provider before starting or stopping any medication.
It is essential for people with VWD to discuss the risks and benefits of any medication with their healthcare professional before starting or changing any medication. Acetaminophen is generally safe for people with VWD, but healthcare professionals may prescribe opioid pain medications and topical pain relief creams.
Emergency preparedness is emphasized for people with VWD. This includes wearing a medical alert bracelet, teaching family and friends how to prepare and administer medication, knowing the location of the closest emergency room or hemophilia treatment center, creating and keeping on hand a "go bag" with items like an emergency care letter, extra medication, and health insurance information, and keeping extra medication and supplies available.
Desmopressin (DDAVP) and factor replacement therapies can help increase VWF and factor VIII in the blood, providing essential support for people with VWD. As always, it is crucial to consult with a healthcare professional for personalised advice and guidance.
